The primary objective of this PhD project is to understand initial reactions to in vitro meat as well as the later processes of framing.
It is expected that the global meat demand will continue to increase in the future, although breeding livestock for meat production has serious disadvantages in terms of sustainability and animal welfare. The production of meat (muscle tissue) from cultured stem cells is a potential and promising alternative.
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For many traits of plants and animals hereditary variation exists in nature. The genetic regulation of such traits is often complex due to their polygenic nature. The model plant Arabidopsis thaliana can be effectively used to dissect these complex traits by using the natural variation present within this species. Until recently genetic analyses were restricted to experimental populations.
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We are a recently founded, internationally oriented group conducting fundamental research on electrostatics and electron transfer in liquid, and simultaneously exploring new concepts for fluidic technologies based on this new understanding. Recent and current research topics include for example carbon nanotube and graphene (bio)sensors, the physics of charge inversion and DNA condensation by multivalent ions, the fundamentals of electrophoresis, high frequency CMOS-based nanosensors, and electrochemical detection of single molecules in nanofluidic devices.
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Background
The peptidoglycan layers surrounding bacteria are essential for bacterial cell survival. Their synthesis in bacteria requires the concerted action of a dynamic and transiently formed network of proteins including inner membrane, periplasmic and even outer membrane proteins in gram-negative bacteria. Besides, cell wall synthesis is tightly linked to cell division, as some cell wall synthesis enzymes have been proven to reside in the divisome, an assembly of proteins that governs cell division.
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Within the research group Hormones and Brain Function (SILS Center for Neuroscience), that will carry out a research project concentrating on the mechanisms involved in the regulation of adult neurogenesis by early-life stress, is a vacancy for a PhD candidate in Neuroscience.
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The candidate will carry out a research project concentrating on the regulation of adult neurogenesis by hormones and microRNAs.
Neurogenesis, the generation of neurons, is a delicately controlled process. In the adult hippocampus, a complex balance of factors keeps it within physiological range. In pathological situations, neurogenesis is aberrantly induced. This is well proven in animal models of epilepsy. This aberrant neurogenesis correlates with hallmarks of epilepsy in the human brain.
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Understanding the role of ancient whole genome duplications (WGD) and subsequent pathway divergence in generating the complexity of life on earth is an important goal of comparative genomics. This project will investigate the potential link between WGDs and key-trait evolution by investigating the glucosinolate defense pathway in the plant order Brassicales.
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